Friday April 15, Malaga

Friday April 15, Malaga

00.01 - 23.59
WCO-IOF-ESCEO
08.00 - 09.00
NON-SPONSORED SYMPOSIA
Meeting Room 1
Preventing future fractures: implementing Fracture Liaison Services throughout the UK
Chairperson: Henry Mace
Model of support for FLS development Henry Mace
Quality improvement Jo Sayer
Socioeconomic costs and benefits Tim Jones
Meeting Room 2
Evaluation of Fracture Risk: beyond DXA and BTMs
Chairperson: Serge Ferrari
Distal bone microstructure Emmanuel Biver
Circulating bone regulatory proteins (Sost, Rankl, postn, ...) Roland D. Chapurlat
Falls risk assessment Andrea Trombetti
Meeting Room 3
Physical activity in treatment and prevention of osteoporosis
Chairperson: Mark Lissens
Introduction Mark Lissens
Importance of physical activity in primary, secondary and tertiary prevention of osteoporosis Olivier Bruyère
Can exercise interventions designed to reduce falls improve bone quality Tash Masud
Specific anti-osteoporotic interventions in patients entering various types of rehabilitation programmes Daniel Uebelhart
Meeting Room 4
Bioactive Collagen Peptides for the Maintenance and Improvement of Musculoskeletal Health
Chairperson: Stephan Scharla
Welcome and introductory presentation Stephan Scharla
Osteoarthritis / Osteoporosis Steffen Oesser
Sarcopenia Daniel König
Meeting Room 5
Inflammatory arthritis and bone health
Chairperson: Elaine M. Dennison
Welcome & Introduction Elaine M. Dennison
Gout and bone health Bo Abrahamsen
HIV arthritis and bone health Karen Walker‑Bone
Novel ways of assessing the relationship between inflammatory arthritis and bone Mark H. Edwards
Discussion Elaine M. Dennison
09.00 - 12.10
Auditorium 1
SCIENTIFIC SESSION I
Chairpersons: John A. Kanis, Jean‑Yves Reginster
09.00
Auditorium 1
Plenary Lecture 1
The Qualities of Bone and Fracture Risk Ego Seeman
09.30
Auditorium 1
Oral communications selected from abstracts
09.30
Auditorium 1
OC1
‣ EFFECTS OF ABALOPARATIDE ON VERTEBRAL, NONVERTEBRAL, MAJOR OSTEOPOROTIC AND CLINICAL FRACTURE INCIDENCE IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS: RESULTS OF THE PHASE 3 ACTIVE TRIAL
Presenting author: L. A. Fitzpatrick
Authors: P. Miller, F. Cosman, D. Black, E. Lau, C. A. F. Zerbini, B. J. Riis, C. Christiansen, G. Williams, H. Hu, G. Hattersley
09.40
Auditorium 1
OC2
‣ EIGHTEEN MONTHS OF TREATMENT WITH ABALOPARATIDE FOLLOWED BY SIX MONTHS OF TREATMENT WITH ALENDRONATE IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS: RESULTS OF THE ACTIVEXTEND TRIAL
Presenting author: S. Ferrari
Authors: F. Cosman, P. Miller, G. Hattersley, G. Williams, H. Hu, B. J. Riis, C. Christiansen, L. A. Fitzpatrick
09.50
Auditorium 1
OC3
‣ SUPERIOR GAINS IN BONE MINERAL DENSITY AND ESTIMATED STRENGTH AT THE HIP FOR ROMOSOZUMAB COMPARED WITH TERIPARATIDE IN WOMEN WITH POSTMENOPAUSAL OSTEOPOROSIS TRANSITIONING FROM BISPHOSPHONATE THERAPY: RESULTS OF THE PHASE 3 OPEN-LABEL STRUCTURE STUDY
Presenting author: J. Malouf
Authors: B. L. Langdahl, C. Libanati, D. B. Crittenden, M. A. Bolognese, J. P. Brown, N. S. Daizadeh, E. Dokoupilova, K. Engelke, J. S. Finkelstein, H. K. Genant, S. Goemaere, L. Hyldstrup, E. Jodar‑Gimeno, T. M.  Keaveny, D. L. Kendler, P.  Lakatos, J. Maddox, F. E. Massari, J. F. Molina, M. R. Ulla, A. Grauer
10.00
Auditorium 1
OC4
‣ A RANDOMIZED DOUBLE-BLIND STUDY OF DENOSUMAB (DMAB) COMPARED WITH ZOLEDRONIC ACID (ZOL) IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS PREVIOUSLY TREATED WITH ORAL BISPHOSPHONATES
Presenting author: J. Malouf
Authors: P. Miller, N. Pannacciulli, J. P. Brown, E. Czerwinski, B. S. Nedergaard, M. A. Bolognese, H. G. Bone, J.‑Y. Reginster, A. Singer, C. Wang, R. B. Wagman, S. R. Cummings
10.10
Auditorium 1
OC5
‣ THE PHASE 3 COMPARISON OF RALOXIFENE AND LASOFOXIFENE (CORAL) TRIAL: CHANGES IN BONE MARKERS AND BONE MINERAL DENSITY
Presenting author: M. R. McClung
Authors: J. Symons, D. Portman
10.20
Auditorium 1
OC6
‣ A RANDOMIZED CONTROLLED TRIAL OF SCREENING IN THE COMMUNITY TO REDUCE FRACTURES IN OLDER WOMEN IN THE UK (THE SCOOP STUDY)
Presenting author: L. Shepstone
Authors: E. Lenaghan, S. Clarke, R. Fordham, N. Gittoes, I. Harvey, R. Holland, A. Howe, T. Marshall, E. V. McCloskey, T. Peters, J. A. Kanis, T. W. O'Neill, D. Torgerson, C. Cooper
10.30
Auditorium 1
Plenary Lecture 2
Offset of fracture risk after treatment cessation, a base for transient treatment interruption Eugene McCloskey
11.00
Auditorium 1
Presentation of the ESCEO-MSD Fellowships
Cyrus Cooper, Anne De Papp
11.10
Auditorium 1
Oral communications selected from abstracts
11.10
Auditorium 1
OC7
‣ EFFECT OF ODANACATIB ON BONE DENSITY AND ESTIMATED BONE STRENGTH IN POSTMENOPAUSAL WOMEN: A CT-BASED SUBSTUDY OF THE PHASE 3 LONG-TERM ODANACATIB FRACTURE TRIAL (LOFT)
Presenting author: K. Engelke
Authors: B. L. Langdahl, T. DeVilliers, T. M.  Keaveny, H. K. Genant, S. Ather, H. Giezek, A. Lombardi, A. Leung, A. De Papp
11.20
Auditorium 1
OC8
‣ PREVENTING BONE LOSS UPON STOPPING DENOSUMAB THERAPY: FINDINGS FROM TWO CLINICAL STUDIES
Presenting author: M. R. McClung
Authors: P. Miller, D. L. Kendler, N. Pannacciulli, A. Wang, R. B. Wagman, S. Ferrari
11.30
Auditorium 1
OC9
‣ PRIOR EXPOSURE TO BISPHOSPHONATES PREVENTS THE REBOUND OF BONE TURNOVER MARKERS AFTER DENOSUMAB THERAPY
Presenting author: B. Uebelhart
Authors: R. Rizzoli, S. Ferrari
11.40
Auditorium 1
OC10
‣ EFFECT OF INVESTIGATIONAL TREATMENT ABALOPARATIDE FOR PREVENTION OF MAJOR OSTEOPOROTIC FRACTURE OR ANY FRACTURE IS NOT ALTERED BY BASELINE FRACTURE PROBABILITY
Presenting author: E. V. McCloskey
Authors: N. C. Harvey, A. Odén, H. Jiang, S. Modin, L. A. Fitzpatrick, J. A. Kanis, H. Johansson
11.50
Auditorium 1
OC11
‣ BONE’S MICROSTRUCTURE AND MATERIAL COMPOSITION ARE COMPROMISED IN WOMEN SUFFERING ATYPICAL FEMORAL FRACTURES DURING ANTIRESORPTIVE THERAPY
Presenting author: E. Seeman
Authors: R. Zebaze, A. Chiang, H. Nguyen, A. Ghasem‑Zadeh, M. Belen Zanchetta, J. R. Zanchetta, P. R. Ebeling
12.00
Auditorium 1
OC12
‣ RISK FOR HIP FRACTURE TEN YEARS BEFORE AND AFTER TOTAL KNEE REPLACEMENT SURGERY IN THE ENTIRE SWEDISH POPULATION
Presenting author: C. H. Vala
Authors: J. Kärrholm, S. Sten, M. Karlsson, V. Sundh, M. Lorentzon, D. Mellström
14.00 - 15.00
Poster Area
Poster Viewing Session I (P100-P450)
14.00 - 15.10
Podium
Oral presentation of selected posters
Chairperson: Johanne Martel‑Pelletier
14.00
Podium
P915
‣ ACCUMULATED QUALITY OF LIFE LOSS 36 MONTHS AFTER VERTEBRAL AND DISTAL FOREARM FRACTURE: RESULTS FROM ICUROS IN LITHUANIA
Presenting author: M. Tamulaitiene
Authors: V. Alekna, F. Borgström, V. Sinkeviciene, A. Svedbom, R. Stukas, J. A. Kanis
14.07
Podium
P836
‣ VERTEBRAL FRACTURE RISK: ALENDRONATE TREATMENT ENHANCES ANTERIOR MICROSTRUCTURE IN OSTEOPOROTIC VERTEBRAE
Presenting author: A. vom Scheidt
Authors: M. Krause, K. Püschel, M. Amling, B.  Busse
14.14
Podium
P829
‣ CATHEPSIN K KNOCKOUT IMPROVES BONE MASS AND SUPPRESSES LONG BONE FRACTURES IN THE OSTEOGENESIS IMPERFECTA MOUSE MODEL (OIM)
Presenting author: T. Roels
Authors: J.‑P. Devogelaer, L. T. Duong, M. Cardinal, C. Behets, D.H. Manicourt
14.21
Podium
P822
‣ LOW-COST AND EFFICIENT FINITE ELEMENT ANALYSIS OF BONE FOR HIGH-RESOLUTION PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY DATA
Presenting author: L. Warren
Authors: M. H. Edwards, Z. Au, K. A. Ward, E. M. Dennison, C. Cooper, P. Schneider
14.28
Podium
P690
‣ IMPACT OF FRACTURE RISK ASSESSMENT TOOLS ON PROPORTIONS OF WOMEN WITHOUT PRIOR FRACTURE IDENTIFIED AT RISK AND TREATED – LESSONS FROM THE SIGN GUIDANCE
Presenting author: E. V. McCloskey
Authors: J. E. Compston, C. Cooper, N. C. Harvey, H. Johansson, A. Odén, J. A. Kanis
14.35
Podium
P492
‣ POST-FRACTURE CARE: DO WE NEED TO EDUCATE THE PATIENTS RATHER THAN THE DOCTORS? THE PREVOST RANDOMIZED CONTROL TRIAL
Presenting author: B. Merle
Authors: R. D. Chapurlat, E. Vignot, T. Thomas, J. Haesebaert, A.‑M. Schott
14.42
Podium
P373
‣ REBOUND-ASSOCIATED VERTEBRAL FRACTURES AFTER DENOSUMAB DISCONTINUATION: A SERIES OF 8 WOMEN WITH 35 SPONTANEOUS VERTEBRAL FRACTURES.
Presenting author: O. Lamy
Authors: D. Stoll, E. Gonzalez Rodriguez, D. Hans, B. Aubry‑Rozier
14.49
Podium
P155
‣ HOW DOES THE INITIAL SLOPE OF THE VARIOGRAM, THE TEXTURAL BASIS OF THE TRABECULAR BONE SCORE, PREDICT VERTEBRAL STRENGTH?
Presenting author: P. K. Zysset
Authors: G. Maquer, Y. Lu, E. Dall'Ara, X. Chevalier, M. Krause, L. Yang, R. Eastell, K. Lippuner
14.56
Podium
P148
‣ THE WNT-INACTIVATING LIPASE NOTUM AS A NOVEL ANABOLIC OSTEOPOROSIS DRUG TARGET
Presenting author: R. Brommage
Authors: A. Y. Thompson, M. K. Shadoan, J. Liu, S. Jeter‑Jones, J. Ciu, D. G.  Potter, D. Bright, F. Mseeh, J. P. Bardenhagan, G. M. Hansen, P. Vogel, J. E.  Tarver, B. Zambrowicz, Q. Liu, D. R. Powell
15.03
Podium
P105
‣ THE IMPACT OF VITAMIN D, CALCIUM, PROTEIN SUPPLEMENTATION, AND PHYSICAL EXERCISE ON BONE METABOLISM AFTER BARIATRIC SURGERY: THE BABS STUDY
Presenting author: H. Resch
Authors: C. Muschitz, R. Kocijan, J. Haschka, A. Zendeli, T. Pirker, G. Muschitz, P. Pietschmann
14.00 - 15.00
MEET-THE-EXPERT SESSIONS
Meeting Room 1
General management of osteoarthritis patients
Burkhard Leeb
Meeting Room 2
Cancer bone disease
Socrates Papapoulos
Meeting Room 3
Management of glucocorticoid-induced osteoporosis
Karel Pavelka
Meeting Room 4
Effective control of inflammatory arthritis
Tore Kvien
Meeting Room 5
Hand osteoarthritis: imaging and management
Emmanuel Maheu
14.00 - 15.00
ESCEO SYMPOSIA
Auditorium 2
ESCEO algorithm for the treatment of osteoarthritis – From evidence-based medicine to real-life setting
Chairpersons: Jean‑Pierre Pelletier, Cyrus Cooper
Welcome address Jean‑Yves Reginster
Efficacy and safety of glucosamine sulfate in the management of osteoarthritis: evidence from real-life setting trials and surveys Jean‑Yves Reginster
Efficacy and safety of oral and topical NSAIDs plus analgesics in the management of osteoarthritis: evidence from real-life setting trials and surveys Jean‑Pierre Pelletier
Efficacy and safety of hyaluronic acid in the management of osteoarthritis: evidence from real-life setting trials and surveys François Rannou
Discussion leaders  Olivier Bruyère, Jaime Branco
Wrap-up and conclusions Cyrus Cooper
Panel: Jaime Branco, Maria Luisa Brandi, Olivier Bruyère, Cyrus Cooper, John A. Kanis, Tore Kvien, Emmanuel Maheu, Johanne Martel‑Pelletier, Jean‑Pierre Pelletier, François Rannou, Jean‑Yves Reginster, René Rizzoli
Conference Room 2.1
Critical analysis of currently available orthopaedic procedures to increase bone mass, structure and strength through intra-osseous interventions
Chairpersons: Andreas Kurth, Dominique Pioletti
Welcome and scope of the problem Serge Ferrari
Current and new tools to assess hip bone strength Philippe K. Zysset
Challenges and opportunities for drug therapies in preventing hip fractures Serge Ferrari
Currently available orthopaedic procedures for bone enhancement Andreas Kurth
Discussion - Leader Maria Luisa Brandi
Wrap-up Serge Ferrari
Adjournment of the meeting John A. Kanis
Panel: Maria Luisa Brandi, Serge Ferrari, John A. Kanis, Andreas Kurth, Andrea Laslop, Socrates Papapoulos, Dominique Pioletti, Jean‑Yves Reginster, René Rizzoli, Philippe K. Zysset
14.00 - 15.00
Conference Room 2.2
EDUCATIONAL LECTURE
Conference Room 2.2
The ABC of writing a manuscript
Ego Seeman
15.00 - 17.00
Auditorium 1
SCIENTIFIC SESSION II
Chairpersons: Maria Luisa Brandi, René Rizzoli
15.00
Auditorium 1
Plenary Lecture 3
Successful musculoskeletal ageing Jonathan D. Adachi
15.30
Auditorium 1
Presentation of the IOF President's Awards
John A. Kanis
15.40
Auditorium 1
Oral communications selected from abstracts
15.40
Auditorium 1
OC13
‣ CORTICAL POROSITY IDENTIFIES WOMEN WITHOUT OSTEOPOROSIS SUFFERING FRAGILITY FRACTURES: THE PROSPECTIVE OFELY STUDY
Presenting author: S. Boutroy
Authors: R. Zebaze, E. Sornay‑Rendu, E. Seeman, R. D. Chapurlat
15.50
Auditorium 1
OC14
‣ BONE MATERIAL STRENGTH INDEX IN PATIENTS WITH LOW BONE MASS AND FRAGILITY FRACTURES
Presenting author: F. Malgo
Authors: S. Papapoulos, N. A. T. Hamdy, N. M. Appelman‑Dijkstra
16.00
Auditorium 1
OC15
‣ RISK AND PREDICTORS OF SUBSEQUENT FRACTURES AFTER AN ATYPICAL FEMORAL FRACTURE
Presenting author: E. Biver
Authors: M.‑C. Audet, R. Peter, R. Meier, D. Uebelhart, T. Chevalley, K. I. Lorenzini, R. Rizzoli, S. Ferrari
16.10
Auditorium 1
OC16
‣ LONGITUDINAL CHANGES IN BONE STRUCTURE AS ASSESSED BY PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY AND RELATIONSHIPS WITH MUSCLE HEALTH IN OLDER MEN AND WOMEN
Presenting author: M. H. Edwards
Authors: K. A. Ward, K. Jameson, E. M. Dennison, C. Cooper
16.20
Auditorium 1
OC17
‣ RELATIONSHIP BETWEEN TOTAL HIP BMD T-SCORE AND INCIDENCE OF NONVERTEBRAL FRACTURE WITH UP TO 10 YEARS OF DENOSUMAB (DMAB) TREATMENT
Presenting author: S. Ferrari
Authors: S. Adami, J. P. Brown, F. Cosman, E. Czerwinski, L. H. De Gregório, J. Malouf, J.‑Y. Reginster, N. S. Daizadeh, A. Wang, R. B. Wagman, E. M. Lewiecki
16.30
Auditorium 1
Plenary Lecture 4
Clinical guidelines for the management of osteoarthritis Cyrus Cooper